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Disrupted PI3K p110δ Signaling Dysregulates Maternal Immune Cells and Increases Fetal Mortality In Mice
Maternal immune cells are an integral part of reproduction, but how they might cause pregnancy complications remains elusive. Macrophages and their dual function in inflammation and tissue repair are thought to play key yet undefined roles. Altered perinatal growth underpins adult morbidity, and nat...
Autores principales: | Kieckbusch, Jens, Balmas, Elisa, Hawkes, Delia A., Colucci, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700049/ https://www.ncbi.nlm.nih.gov/pubmed/26711346 http://dx.doi.org/10.1016/j.celrep.2015.11.050 |
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