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Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD

BACKGROUND: Respiratory virus infections are commonly associated with COPD exacerbations, but little is known about the mechanisms linking virus infection to exacerbations. Pathogenic mechanisms in stable COPD include oxidative and nitrosative stress and reduced activity of histone deacetylase-2 (HD...

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Detalles Bibliográficos
Autores principales: Footitt, Joseph, Mallia, Patrick, Durham, Andrew L., Ho, W. Eugene, Trujillo-Torralbo, Maria-Belen, Telcian, Aurica G., Del Rosario, Ajerico, Chang, Cheng, Peh, Hong-Yong, Kebadze, Tatiana, Aniscenko, Julia, Stanciu, Luminita, Essilfie-Quaye, Sarah, Ito, Kazuhiro, Barnes, Peter J., Elkin, Sarah L., Kon, Onn M., Wong, W. S. Fred, Adcock, Ian M., Johnston, Sebastian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Chest Physicians 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700054/
https://www.ncbi.nlm.nih.gov/pubmed/25790167
http://dx.doi.org/10.1378/chest.14-2637