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Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD
BACKGROUND: Respiratory virus infections are commonly associated with COPD exacerbations, but little is known about the mechanisms linking virus infection to exacerbations. Pathogenic mechanisms in stable COPD include oxidative and nitrosative stress and reduced activity of histone deacetylase-2 (HD...
Autores principales: | Footitt, Joseph, Mallia, Patrick, Durham, Andrew L., Ho, W. Eugene, Trujillo-Torralbo, Maria-Belen, Telcian, Aurica G., Del Rosario, Ajerico, Chang, Cheng, Peh, Hong-Yong, Kebadze, Tatiana, Aniscenko, Julia, Stanciu, Luminita, Essilfie-Quaye, Sarah, Ito, Kazuhiro, Barnes, Peter J., Elkin, Sarah L., Kon, Onn M., Wong, W. S. Fred, Adcock, Ian M., Johnston, Sebastian L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American College of Chest Physicians
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700054/ https://www.ncbi.nlm.nih.gov/pubmed/25790167 http://dx.doi.org/10.1378/chest.14-2637 |
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