Cargando…

Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

Alzheimer’s disease (AD) is an age-related neurodegenerative disease marked by a progressive cognitive decline. Metabolic impairments are common hallmarks of AD, and amyloid-β (Aβ) peptide and hyperphosphorylated tau protein—the two foremost histopathological signs of AD—have been implicated in mito...

Descripción completa

Detalles Bibliográficos
Autores principales: Grimm, Amandine, Biliouris, Emily E., Lang, Undine E., Götz, Jürgen, Mensah-Nyagan, Ayikoe Guy, Eckert, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700074/
https://www.ncbi.nlm.nih.gov/pubmed/26198711
http://dx.doi.org/10.1007/s00018-015-1988-x