The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence

High uniform fluid shear stress (FSS) is atheroprotective and preserves the endothelial phenotype and function through activation of downstream mediators such as MAPK7 (Erk5). Endothelial cells respond to FSS thanks to mechanotransduction. However, how the resulting signaling is integrated and resol...

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Detalles Bibliográficos
Autores principales: Maleszewska, Monika, Vanchin, Byambasuren, Harmsen, Martin C., Krenning, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700080/
https://www.ncbi.nlm.nih.gov/pubmed/26416763
http://dx.doi.org/10.1007/s10456-015-9485-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700080/
https://www.ncbi.nlm.nih.gov/pubmed/26416763
http://dx.doi.org/10.1007/s10456-015-9485-2

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