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Andrographolide Stimulates Neurogenesis in the Adult Hippocampus

Andrographolide (ANDRO) is a labdane diterpenoid component of Andrographis paniculata widely used for its anti-inflammatory properties. We have recently determined that ANDRO is a competitive inhibitor of glycogen synthase kinase-3β (GSK-3β), a key enzyme of the Wnt/β-catenin signaling cascade. Sinc...

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Detalles Bibliográficos
Autores principales: Varela-Nallar, Lorena, Arredondo, Sebastian B., Tapia-Rojas, Cheril, Hancke, Juan, Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700200/
https://www.ncbi.nlm.nih.gov/pubmed/26798521
http://dx.doi.org/10.1155/2015/935403