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Andrographolide Stimulates Neurogenesis in the Adult Hippocampus
Andrographolide (ANDRO) is a labdane diterpenoid component of Andrographis paniculata widely used for its anti-inflammatory properties. We have recently determined that ANDRO is a competitive inhibitor of glycogen synthase kinase-3β (GSK-3β), a key enzyme of the Wnt/β-catenin signaling cascade. Sinc...
Autores principales: | Varela-Nallar, Lorena, Arredondo, Sebastian B., Tapia-Rojas, Cheril, Hancke, Juan, Inestrosa, Nibaldo C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700200/ https://www.ncbi.nlm.nih.gov/pubmed/26798521 http://dx.doi.org/10.1155/2015/935403 |
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