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DNA Demethylation Upregulated Nrf2 Expression in Alzheimer’s Disease Cellular Model

Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important transcription factor in the defense against oxidative stress. Cumulative evidence has shown that oxidative stress plays a key role in the pathogenesis of Alzheimer’s disease (AD). Previous animal and clinical studies had observed dec...

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Detalles Bibliográficos
Autores principales: Cao, Huimin, Wang, Li, Chen, Beibei, Zheng, Peng, He, Yi, Ding, Yubin, Deng, Yushuang, Lu, Xi, Guo, Xiuming, Zhang, Yuping, Li, Yu, Yu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700271/
https://www.ncbi.nlm.nih.gov/pubmed/26779013
http://dx.doi.org/10.3389/fnagi.2015.00244