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Withaferin A Inhibits Helicobacter pylori-induced Production of IL-1β in Dendritic Cells by Regulating NF-κB and NLRP3 Inflammasome Activation

Helicobacter pylori infection is associated with chronic gastritis, peptic ulcer, and gastric cancer. There is evidence that IL-1β is associated with the development of gastric cancer. Therefore, downregulation of H. pylori-mediated IL-1β production may be a way to prevent gastric cancer. Withaferin...

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Detalles Bibliográficos
Autores principales: Kim, Jae-Eun, Lee, Jun-Young, Kang, Min-Jung, Jeong, Yu-Jin, Choi, Jin-A, Oh, Sang-Muk, Lee, Kyung-Bok, Park, Jong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700403/
https://www.ncbi.nlm.nih.gov/pubmed/26770181
http://dx.doi.org/10.4110/in.2015.15.6.269