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The Anti-inflammatory Effect of GV1001 Mediated by the Downregulation of ENO1-induced Pro-inflammatory Cytokine Production

GV1001 is a peptide derived from the human telomerase reverse transcriptase (hTERT) sequence that is reported to have anti-cancer and anti-inflammatory effects. Enolase1 (ENO1) is a glycolytic enzyme, and stimulation of this enzyme induces high levels of pro-inflammatory cytokines from concanavalin...

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Detalles Bibliográficos
Autores principales: Choi, Jiyea, Kim, Hyemin, Kim, Yejin, Jang, Mirim, Jeon, Jane, Hwang, Young-il, Shon, Won Jun, Song, Yeong Wook, Kang, Jae Seung, Lee, Wang Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700405/
https://www.ncbi.nlm.nih.gov/pubmed/26770183
http://dx.doi.org/10.4110/in.2015.15.6.291