Topographic confinement of epithelial clusters induces epithelial-to-mesenchymal transition in compliant matrices

Epithelial cells disengage from their clusters and become motile by undergoing epithelial-to-mesenchymal transition (EMT), an essential process for both embryonic development and tumor metastasis. Growing evidence suggests that high extracellular matrix (ECM) stiffness induces EMT. In reality, epith...

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Detalles Bibliográficos
Autores principales: Nasrollahi, Samila, Pathak, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700414/
https://www.ncbi.nlm.nih.gov/pubmed/26728047
http://dx.doi.org/10.1038/srep18831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700414/
https://www.ncbi.nlm.nih.gov/pubmed/26728047
http://dx.doi.org/10.1038/srep18831

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