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Topographic confinement of epithelial clusters induces epithelial-to-mesenchymal transition in compliant matrices
Epithelial cells disengage from their clusters and become motile by undergoing epithelial-to-mesenchymal transition (EMT), an essential process for both embryonic development and tumor metastasis. Growing evidence suggests that high extracellular matrix (ECM) stiffness induces EMT. In reality, epith...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700414/ https://www.ncbi.nlm.nih.gov/pubmed/26728047 http://dx.doi.org/10.1038/srep18831 |