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AGE-RAGE signal generates a specific NF-κB RelA “barcode” that directs collagen I expression

Advanced glycation end products (AGEs) are sugar-modified biomolecules that accumulate in the body with advancing age, and are implicated in the development of multiple age-associated structural and functional abnormities and diseases. It has been well documented that AGEs signal via their receptor...

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Detalles Bibliográficos
Autores principales: Peng, Yunqian, Kim, Ji-Min, Park, Hal-Sol, Yang, Annie, Islam, Celia, Lakatta, Edward G., Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700418/
https://www.ncbi.nlm.nih.gov/pubmed/26729520
http://dx.doi.org/10.1038/srep18822