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Farnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming

Farnesoid X receptor (FXR) plays a pivotal role in the regulation of various metabolic pathways as well as liver regeneration. However, the casual link between cell proliferative effects during liver regeneration and metabolic regulation of FXR was elusive. In this study, we found that FXR activatio...

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Detalles Bibliográficos
Autores principales: Xie, Yang, Wang, Hong, Cheng, Xuefang, Wu, Yuzheng, Cao, Lijuan, Wu, Mengqiu, Xie, Wen, Wang, Guangji, Hao, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700422/
https://www.ncbi.nlm.nih.gov/pubmed/26728993
http://dx.doi.org/10.1038/srep18751