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Farnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming
Farnesoid X receptor (FXR) plays a pivotal role in the regulation of various metabolic pathways as well as liver regeneration. However, the casual link between cell proliferative effects during liver regeneration and metabolic regulation of FXR was elusive. In this study, we found that FXR activatio...
Autores principales: | Xie, Yang, Wang, Hong, Cheng, Xuefang, Wu, Yuzheng, Cao, Lijuan, Wu, Mengqiu, Xie, Wen, Wang, Guangji, Hao, Haiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700422/ https://www.ncbi.nlm.nih.gov/pubmed/26728993 http://dx.doi.org/10.1038/srep18751 |
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