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Apoptosis signal-regulating kinase 1 mediates striatal degeneration via the regulation of C1q

Apoptosis signal-regulating kinase-1 (ASK1), an early signaling element in the cell death pathway, has been hypothesized to participate in the pathology of neurodegenerative diseases. The systemic administration of 3-nitropropionic acid (3-NP) facilitates the development of selective striatal lesion...

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Detalles Bibliográficos
Autores principales: Cho, Kyoung Joo, Cheon, So Young, Kim, Gyung Whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700432/
https://www.ncbi.nlm.nih.gov/pubmed/26728245
http://dx.doi.org/10.1038/srep18840