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Apoptosis signal-regulating kinase 1 mediates striatal degeneration via the regulation of C1q
Apoptosis signal-regulating kinase-1 (ASK1), an early signaling element in the cell death pathway, has been hypothesized to participate in the pathology of neurodegenerative diseases. The systemic administration of 3-nitropropionic acid (3-NP) facilitates the development of selective striatal lesion...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700432/ https://www.ncbi.nlm.nih.gov/pubmed/26728245 http://dx.doi.org/10.1038/srep18840 |