Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells

An aberrant expression of integrin β1 has been implicated in breast cancer progression. Here, we compared the cell behaviors of wild-type (WT), β1 gene deleted (KO), and β1 gene restored (Res) MDA-MB-231 cells. Surprisingly, the expression of β1 exhibited opposite effects on cell proliferation. Thes...

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Detalles Bibliográficos
Autores principales: Hou, Sicong, Isaji, Tomoya, Hang, Qinglei, Im, Sanghun, Fukuda, Tomohiko, Gu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700444/
https://www.ncbi.nlm.nih.gov/pubmed/26728650
http://dx.doi.org/10.1038/srep18430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700444/
https://www.ncbi.nlm.nih.gov/pubmed/26728650
http://dx.doi.org/10.1038/srep18430

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