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Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium
During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into specialized cell types. We show that the Polycomb component Cbx4 serves as a critical determinant that maintains the epithelial identity in t...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700479/ https://www.ncbi.nlm.nih.gov/pubmed/26711500 http://dx.doi.org/10.1083/jcb.201506065 |