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PML isoform II plays a critical role in nuclear lipid droplet formation

Lipid droplets (LDs) in the nucleus of hepatocyte-derived cell lines were found to be associated with premyelocytic leukemia (PML) nuclear bodies (NBs) and type I nucleoplasmic reticulum (NR) or the extension of the inner nuclear membrane. Knockdown of PML isoform II (PML-II) caused a significant de...

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Detalles Bibliográficos
Autores principales: Ohsaki, Yuki, Kawai, Takeshi, Yoshikawa, Yukichika, Cheng, Jinglei, Jokitalo, Eija, Fujimoto, Toyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700481/
https://www.ncbi.nlm.nih.gov/pubmed/26728854
http://dx.doi.org/10.1083/jcb.201507122