Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease

Altered brain metabolism is associated with progression of Alzheimer’s Disease (AD). Mitochondria respond to bioenergetic changes by continuous fission and fusion. To account for three dimensional architecture of the brain tissue and organelles, we applied 3-dimensional electron microscopy (3D EM) r...

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Detalles Bibliográficos
Autores principales: Zhang, Liang, Trushin, Sergey, Christensen, Trace A., Bachmeier, Benjamin V., Gateno, Benjamin, Schroeder, Andreas, Yao, Jia, Itoh, Kie, Sesaki, Hiromi, Poon, Wayne W., Gylys, Karen H., Patterson, Emily R., Parisi, Joseph E., Diaz Brinton, Roberta, Salisbury, Jeffrey L., Trushina, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700525/
https://www.ncbi.nlm.nih.gov/pubmed/26729583
http://dx.doi.org/10.1038/srep18725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700525/
https://www.ncbi.nlm.nih.gov/pubmed/26729583
http://dx.doi.org/10.1038/srep18725

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