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Restriction of protein synthesis abolishes senescence features at cellular and organismal levels
Cellular senescence or its equivalence is induced by treatment of cells with an appropriate inducer of senescence in various cell types. Mild restriction of cytoplasmic protein synthesis prevented induction of all aspects of cellular senescence in normal and tumor-derived human cells. It allowed the...
Autores principales: | Takauji, Yuki, Wada, Takumi, Takeda, Asuka, Kudo, Ikuru, Miki, Kensuke, Fujii, Michihiko, Ayusawa, Dai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700526/ https://www.ncbi.nlm.nih.gov/pubmed/26729469 http://dx.doi.org/10.1038/srep18722 |
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