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Serum Autotaxin/ENPP2 Correlates with Insulin Resistance in Older Humans with Obesity

OBJECTIVE: Autotaxin (ATX) is an adipocyte-derived lysophospholipase D that generates the lipid signaling molecule lysophosphatidic acid (LPA). The ATX/LPA pathway in adipose tissue has recently been implicated in obesity and insulin resistance in animal models, but the role of circulating ATX in hu...

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Detalles Bibliográficos
Autores principales: Reeves, Valerie L., Trybula, Joy S., Wills, Rachel C., Goodpaster, Bret H., Dubé, John J., Kienesberger, Petra C., Kershaw, Erin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700540/
https://www.ncbi.nlm.nih.gov/pubmed/26727116
http://dx.doi.org/10.1002/oby.21232