HPV 16E7 and 48E7 proteins use different mechanisms to target p130 to overcome cell cycle block

BACKGROUND: Retinoblastoma like protein 2 (RBL2) or p130 is a member of the pocket protein family, which is infrequently mutated in human tumours. Its expression is posttranscriptionally regulated and largely G0 restricted. We have previously shown that E6/E7 oncoproteins encoded by human papillomav...

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Detalles Bibliográficos
Autores principales: Nor Rashid, Nurshamimi, Yong, Zi Ling, Yusof, Rohana, Watson, Roger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700559/
https://www.ncbi.nlm.nih.gov/pubmed/26728921
http://dx.doi.org/10.1186/s12985-015-0460-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700559/
https://www.ncbi.nlm.nih.gov/pubmed/26728921
http://dx.doi.org/10.1186/s12985-015-0460-8

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