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HPV 16E7 and 48E7 proteins use different mechanisms to target p130 to overcome cell cycle block
BACKGROUND: Retinoblastoma like protein 2 (RBL2) or p130 is a member of the pocket protein family, which is infrequently mutated in human tumours. Its expression is posttranscriptionally regulated and largely G0 restricted. We have previously shown that E6/E7 oncoproteins encoded by human papillomav...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700559/ https://www.ncbi.nlm.nih.gov/pubmed/26728921 http://dx.doi.org/10.1186/s12985-015-0460-8 |