Cargando…

Subtype-specific accumulation of intracellular zinc pools is associated with the malignant phenotype in breast cancer

BACKGROUND: Zinc (Zn) hyper-accumulates in breast tumors and malignant cell lines compared to normal mammary epithelium. The mechanisms responsible for Zn accumulation and the consequence of Zn dysregulation are poorly understood. METHODS: Microarrays were performed to assess differences in the expr...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandler, Paige, Kochupurakkal, Bose S., Alam, Samina, Richardson, Andrea L., Soybel, David I., Kelleher, Shannon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700748/
https://www.ncbi.nlm.nih.gov/pubmed/26728511
http://dx.doi.org/10.1186/s12943-015-0486-y