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Subtype-specific accumulation of intracellular zinc pools is associated with the malignant phenotype in breast cancer
BACKGROUND: Zinc (Zn) hyper-accumulates in breast tumors and malignant cell lines compared to normal mammary epithelium. The mechanisms responsible for Zn accumulation and the consequence of Zn dysregulation are poorly understood. METHODS: Microarrays were performed to assess differences in the expr...
Autores principales: | Chandler, Paige, Kochupurakkal, Bose S., Alam, Samina, Richardson, Andrea L., Soybel, David I., Kelleher, Shannon L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700748/ https://www.ncbi.nlm.nih.gov/pubmed/26728511 http://dx.doi.org/10.1186/s12943-015-0486-y |
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