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Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells

BACKGROUND: In the initiation and maintenance of arrhythmia, inflammatory processes play an important role. IL-2 is a pro-inflammatory factor which is associated with the morbidity of arrhythmias, however, how IL-2 affects the cardiac electrophysiology is still unknown. METHODS: In the present study...

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Detalles Bibliográficos
Autores principales: Zhao, Yuanyuan, Sun, Qiaobing, Zeng, Zhipeng, Li, Qianqian, Zhou, Shiyuan, Zhou, Mengchen, Xue, Yumei, Cheng, Xiang, Xia, Yunlong, Wang, Qing, Tu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700781/
https://www.ncbi.nlm.nih.gov/pubmed/26728597
http://dx.doi.org/10.1186/s12872-015-0179-x