Inferring Indel Parameters using a Simulation-based Approach

In this study, we present a novel methodology to infer indel parameters from multiple sequence alignments (MSAs) based on simulations. Our algorithm searches for the set of evolutionary parameters describing indel dynamics which best fits a given input MSA. In each step of the search, we use paramet...

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Detalles Bibliográficos
Autores principales: Levy Karin, Eli, Rabin, Avigayel, Ashkenazy, Haim, Shkedy, Dafna, Avram, Oren, Cartwright, Reed A., Pupko, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700945/
https://www.ncbi.nlm.nih.gov/pubmed/26537226
http://dx.doi.org/10.1093/gbe/evv212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700945/
https://www.ncbi.nlm.nih.gov/pubmed/26537226
http://dx.doi.org/10.1093/gbe/evv212

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