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Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain
The comparative genomics revolution of the past decade has enabled the discovery of functional elements in the human genome via sequence comparison. While that is so, an important class of elements, those specific to humans, is entirely missed by searching for sequence conservation across species. H...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700959/ https://www.ncbi.nlm.nih.gov/pubmed/26590212 http://dx.doi.org/10.1093/gbe/evv228 |