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K(+) Block Is the Mechanism of Functional Asymmetry in Bacterial Na(v) Channels

Crystal structures of several bacterial Na(v) channels have been recently published and molecular dynamics simulations of ion permeation through these channels are consistent with many electrophysiological properties of eukaryotic channels. Bacterial Na(v) channels have been characterized as functio...

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Detalles Bibliográficos
Autores principales: Ngo, Van, Wang, Yibo, Haas, Stephan, Noskov, Sergei Y., Farley, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700994/
https://www.ncbi.nlm.nih.gov/pubmed/26727271
http://dx.doi.org/10.1371/journal.pcbi.1004482