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Neuraminidase-Dependent Degradation of Polysialic Acid Is Required for the Lamination of Newly Generated Neurons

Hippocampal granule cells (GCs) are generated throughout the lifetime and are properly incorporated into the innermost region of the granule cell layer (GCL). Hypotheses for the well-regulated lamination of newly generated GCs suggest that polysialic acid (PSA) is present on the GC surface to modula...

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Detalles Bibliográficos
Autores principales: Sajo, Mari, Sugiyama, Hiroki, Yamamoto, Hideaki, Tanii, Takashi, Matsuki, Norio, Ikegaya, Yuji, Koyama, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701216/
https://www.ncbi.nlm.nih.gov/pubmed/26731280
http://dx.doi.org/10.1371/journal.pone.0146398