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Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice

Autism spectrum disorders (ASDs) are a group of neurodevelopmental afflictions characterized by repetitive behaviors, deficits in social interaction, and impaired communication skills. For most ASD patients, the underlying causes are unknown. Genetic mutations have been identified in about 25 percen...

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Detalles Bibliográficos
Autores principales: Zheng, Fei, Kasper, Lawryn H., Bedford, David C., Lerach, Stephanie, Teubner, Brett J. W., Brindle, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701386/
https://www.ncbi.nlm.nih.gov/pubmed/26730956
http://dx.doi.org/10.1371/journal.pone.0146366