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High-accuracy biodistribution analysis of adeno-associated virus variants by double barcode sequencing
Biodistribution analysis is a key step in the evaluation of adeno-associated virus (AAV) capsid variants, whether natural isolates or produced by rational design or directed evolution. Indeed, when screening candidate vectors, accurate knowledge about which tissues are infected and how efficiently i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701405/ https://www.ncbi.nlm.nih.gov/pubmed/26793739 http://dx.doi.org/10.1038/mtm.2015.41 |