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High-accuracy biodistribution analysis of adeno-associated virus variants by double barcode sequencing

Biodistribution analysis is a key step in the evaluation of adeno-associated virus (AAV) capsid variants, whether natural isolates or produced by rational design or directed evolution. Indeed, when screening candidate vectors, accurate knowledge about which tissues are infected and how efficiently i...

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Detalles Bibliográficos
Autores principales:	Marsic, Damien, Méndez-Gómez, Héctor R, Zolotukhin, Sergei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701405/ https://www.ncbi.nlm.nih.gov/pubmed/26793739 http://dx.doi.org/10.1038/mtm.2015.41

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