Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase

Affinity reagents of high affinity and specificity are very useful for studying the subcellular locations and quantities of individual proteins. To generate high-quality affinity reagents for human Lyn tyrosine kinase, a phage display library of fibronectin type III (FN3) monobodies was affinity sel...

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Detalles Bibliográficos
Autores principales: Huang, Renhua, Fang, Pete, Hao, Zengping, Kay, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701441/
https://www.ncbi.nlm.nih.gov/pubmed/26731115
http://dx.doi.org/10.1371/journal.pone.0145872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701441/
https://www.ncbi.nlm.nih.gov/pubmed/26731115
http://dx.doi.org/10.1371/journal.pone.0145872

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