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High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes

New strategies are needed to address the data gap between the bioactivity of chemicals in the environment versus existing hazard information. We address whether a high-throughput screening (HTS) system using a vertebrate organism (embryonic zebrafish) can characterize chemical-elicited behavioral re...

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Detalles Bibliográficos
Autores principales: Reif, David M., Truong, Lisa, Mandrell, David, Marvel, Skylar, Zhang, Guozhu, Tanguay, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701642/
https://www.ncbi.nlm.nih.gov/pubmed/26126630
http://dx.doi.org/10.1007/s00204-015-1554-1