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Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation

Host control of influenza A virus (IAV) is associated with exuberant pulmonary inflammation characterized by the influx of myeloid cells and production of proinflammatory cytokines including interferons (IFNs). It is unclear, however, how the immune system clears the virus without causing lethal imm...

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Detalles Bibliográficos
Autores principales: Stifter, Sebastian A., Bhattacharyya, Nayan, Pillay, Roman, Flórido, Manuela, Triccas, James A., Britton, Warwick J., Feng, Carl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701664/
https://www.ncbi.nlm.nih.gov/pubmed/26731100
http://dx.doi.org/10.1371/journal.ppat.1005378