LPS-Primed Release of HMGB-1 from Cortical Astrocytes is Modulated Through PI3K/AKT Pathway

Studies have shown that LPS-preconditioned tolerant state could protect against brain injury to subsequent challenges. We hypothesized astrocytes were directly involved in the readjustment to confer neuroprotective effects with LPS pretreatment. High-mobility group box 1(HMGB-1) from LPS-preconditio...

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Detalles Bibliográficos
Autores principales: Xie, Ze-Feng, Xin, Gang, Xu, Yan-Xuan, Su, Yun, Li, Kang-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701761/
https://www.ncbi.nlm.nih.gov/pubmed/26115623
http://dx.doi.org/10.1007/s10571-015-0223-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701761/
https://www.ncbi.nlm.nih.gov/pubmed/26115623
http://dx.doi.org/10.1007/s10571-015-0223-5

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