Disruptions in a cluster of computationally identified enhancers near FOXC1 and GMDS may influence brain development

Regulatory elements are more evolutionarily conserved and provide a larger mutational target than coding regions of the human genome, suggesting that mutations in non-coding regions contribute significantly to development and disease. Using a computational approach to predict gene regulatory enhance...

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Detalles Bibliográficos
Autores principales: Haliburton, Genevieve D. E., McKinsey, Gabriel L., Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701781/
https://www.ncbi.nlm.nih.gov/pubmed/26382291
http://dx.doi.org/10.1007/s10048-015-0458-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701781/
https://www.ncbi.nlm.nih.gov/pubmed/26382291
http://dx.doi.org/10.1007/s10048-015-0458-9

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