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Disruptions in a cluster of computationally identified enhancers near FOXC1 and GMDS may influence brain development
Regulatory elements are more evolutionarily conserved and provide a larger mutational target than coding regions of the human genome, suggesting that mutations in non-coding regions contribute significantly to development and disease. Using a computational approach to predict gene regulatory enhance...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701781/ https://www.ncbi.nlm.nih.gov/pubmed/26382291 http://dx.doi.org/10.1007/s10048-015-0458-9 |