Plasma pharmacokinetics and synovial concentrations of S-flurbiprofen plaster in humans

PURPOSE: The purpose of this study is to investigate the pharmacokinetics and deep tissue penetration capability of the newly developed S-flurbiprofen plaster (SFPP) in humans. METHODS: Study 1: SFPP tape-type patch (2–60 mg) was applied to the lower back for 24 h in healthy adult volunteers. S-flur...

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Detalles Bibliográficos
Autores principales: Yataba, Ikuko, Otsuka, Noboru, Matsushita, Isao, Kamezawa, Miho, Yamada, Ichimaro, Sasaki, Sigeru, Uebaba, Kazuo, Matsumoto, Hideo, Hoshino, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701782/
https://www.ncbi.nlm.nih.gov/pubmed/26438533
http://dx.doi.org/10.1007/s00228-015-1960-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701782/
https://www.ncbi.nlm.nih.gov/pubmed/26438533
http://dx.doi.org/10.1007/s00228-015-1960-6

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