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Plasma pharmacokinetics and synovial concentrations of S-flurbiprofen plaster in humans

PURPOSE: The purpose of this study is to investigate the pharmacokinetics and deep tissue penetration capability of the newly developed S-flurbiprofen plaster (SFPP) in humans. METHODS: Study 1: SFPP tape-type patch (2–60 mg) was applied to the lower back for 24 h in healthy adult volunteers. S-flur...

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Detalles Bibliográficos
Autores principales:	Yataba, Ikuko, Otsuka, Noboru, Matsushita, Isao, Kamezawa, Miho, Yamada, Ichimaro, Sasaki, Sigeru, Uebaba, Kazuo, Matsumoto, Hideo, Hoshino, Yuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Pharmacokinetics and Disposition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701782/ https://www.ncbi.nlm.nih.gov/pubmed/26438533 http://dx.doi.org/10.1007/s00228-015-1960-6

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