Cargando…

Dosage and Dose Schedule Screening of Drug Combinations in Agent-Based Models Reveals Hidden Synergies

The fungus Candida albicans is the most common causative agent of human fungal infections and better drugs or drug combination strategies are urgently needed. Here, we present an agent-based model of the interplay of C. albicans with the host immune system and with the microflora of the host. We too...

Descripción completa

Detalles Bibliográficos
Autores principales: Barros de Andrade e Sousa, Lisa C., Kühn, Clemens, Tyc, Katarzyna M., Klipp, Edda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701919/
https://www.ncbi.nlm.nih.gov/pubmed/26779031
http://dx.doi.org/10.3389/fphys.2015.00398