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Dosage and Dose Schedule Screening of Drug Combinations in Agent-Based Models Reveals Hidden Synergies
The fungus Candida albicans is the most common causative agent of human fungal infections and better drugs or drug combination strategies are urgently needed. Here, we present an agent-based model of the interplay of C. albicans with the host immune system and with the microflora of the host. We too...
Autores principales: | Barros de Andrade e Sousa, Lisa C., Kühn, Clemens, Tyc, Katarzyna M., Klipp, Edda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701919/ https://www.ncbi.nlm.nih.gov/pubmed/26779031 http://dx.doi.org/10.3389/fphys.2015.00398 |
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