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BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance
Melanoma can switch between proliferative and invasive states, which have identifying gene expression signatures that correlate with good and poor prognosis, respectively. However, the mechanisms controlling these signatures are poorly understood. In this study, we identify BMI1 as a key determinant...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701976/ https://www.ncbi.nlm.nih.gov/pubmed/26679841 http://dx.doi.org/10.1101/gad.267757.115 |