Cargando…

BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance

Melanoma can switch between proliferative and invasive states, which have identifying gene expression signatures that correlate with good and poor prognosis, respectively. However, the mechanisms controlling these signatures are poorly understood. In this study, we identify BMI1 as a key determinant...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferretti, Roberta, Bhutkar, Arjun, McNamara, Molly C., Lees, Jacqueline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701976/
https://www.ncbi.nlm.nih.gov/pubmed/26679841
http://dx.doi.org/10.1101/gad.267757.115