Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine

Reactive oxygen species (ROS) participate in numerous cell responses, including proliferation, DNA damage, and cell death. Based on these disparate activities, both promotion and inhibition of ROS have been proposed for cancer therapy. However, how the ROS response is determined is not clear. We exa...

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Detalles Bibliográficos
Autores principales: Cheung, Eric C., Lee, Pearl, Ceteci, Fatih, Nixon, Colin, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701978/
https://www.ncbi.nlm.nih.gov/pubmed/26679840
http://dx.doi.org/10.1101/gad.271130.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701978/
https://www.ncbi.nlm.nih.gov/pubmed/26679840
http://dx.doi.org/10.1101/gad.271130.115

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