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p53 genes function to restrain mobile elements

Throughout the animal kingdom, p53 genes govern stress response networks by specifying adaptive transcriptional responses. The human member of this gene family is mutated in most cancers, but precisely how p53 functions to mediate tumor suppression is not well understood. Using Drosophila and zebraf...

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Detalles Bibliográficos
Autores principales: Wylie, Annika, Jones, Amanda E., D'Brot, Alejandro, Lu, Wan-Jin, Kurtz, Paula, Moran, John V., Rakheja, Dinesh, Chen, Kenneth S., Hammer, Robert E., Comerford, Sarah A., Amatruda, James F., Abrams, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701979/
https://www.ncbi.nlm.nih.gov/pubmed/26701264
http://dx.doi.org/10.1101/gad.266098.115