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p53 genes function to restrain mobile elements
Throughout the animal kingdom, p53 genes govern stress response networks by specifying adaptive transcriptional responses. The human member of this gene family is mutated in most cancers, but precisely how p53 functions to mediate tumor suppression is not well understood. Using Drosophila and zebraf...
Autores principales: | Wylie, Annika, Jones, Amanda E., D'Brot, Alejandro, Lu, Wan-Jin, Kurtz, Paula, Moran, John V., Rakheja, Dinesh, Chen, Kenneth S., Hammer, Robert E., Comerford, Sarah A., Amatruda, James F., Abrams, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701979/ https://www.ncbi.nlm.nih.gov/pubmed/26701264 http://dx.doi.org/10.1101/gad.266098.115 |
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