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FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling

BACKGROUND: FAT4, a cadherin-related protein, was shown to function as a tumour suppressor; however, its role in human gastric cancer remains largely unknown. Here, we investigated the role of FAT4 in gastric cancer and examined the underlying molecular mechanisms. METHODS: The expression of FAT4 wa...

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Detalles Bibliográficos
Autores principales: Cai, Jian, Feng, Dan, Hu, Liang, Chen, Haiyang, Yang, Guangzhen, Cai, Qingping, Gao, Chunfang, Wei, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701992/
https://www.ncbi.nlm.nih.gov/pubmed/26633557
http://dx.doi.org/10.1038/bjc.2015.367